Safer ventilation of the injured lung: one step closer

نویسنده

  • John J Marini
چکیده

Prevention of iatrogenic injury due to ventilation of a heterogeneous lung requires knowledge of dynamic regional events occurring within the tidal cycle. Quantitative bedside imaging techniques that are sensitive to regional mechanics and tidal events hold potential for information delivery that cannot be realized by pressure-volume monitoring alone.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Metagenomic Analysis of Lung Microbiome in Chemically Injured and Healthy Individuals

Background and Aim: The role of the lung microbiome in respiratory complications associated with chemicals such as sulfur mustard or chlorine gas has yet to be determined. The aim of this study was to compare the structure and composition of the lung microbiome in chemically injured and healthy individuals in order to understand the relation between the population of the lung microbiota and res...

متن کامل

Spurious lung perfusion ventilation defect on planar ventilation-perfusion scan detected by SPECT imaging

Pulmonary embolism (PE) is a preventable cause of morbidity and mortality which needs prompt recognition. Ventilation-perfusion (V/Q) scan is a well-established diagnostic test for evaluation of suspected PE. We report a 32-year-old woman with history of rheumatologic disease and acute dyspnea, who was referred for V/Q scintigraphy. The planar images revealed multiple mismatched defects through...

متن کامل

Mechanical Ventilation Injury and Repair in Extremely and Very Preterm Lungs

BACKGROUND Extremely preterm infants often receive mechanical ventilation (MV), which can contribute to bronchopulmonary dysplasia (BPD). However, the effects of MV alone on the extremely preterm lung and the lung's capacity for repair are poorly understood. AIM To characterise lung injury induced by MV alone, and mechanisms of injury and repair, in extremely preterm lungs and to compare them...

متن کامل

Diagnosis of thromboembolic disease: Combined ventilation perfusion lung scan and compression ultrasonography

The clinical management of pulmonary embolism and deep venous thrombosis of the legs are similar and requires prolonged anticoagulation therapy. The standard diagnostic approach in patients suspected of pulmonary embolism is ventilation-perfusion (V/Q) lung scan and compression ultrasonography to detect deep venous thrombosis. This retrospective study analyzed the role of V/Q lung scan an...

متن کامل

Design of a new variable-ventilation method optimized for lung recruitment in mice.

Variable ventilation (VV), characterized by breath-to-breath variation of tidal volume (Vt) and breathing rate (f), has been shown to improve lung mechanics and blood oxygenation during acute lung injury in many species compared with conventional ventilation (CV), characterized by constant Vt and f. During CV as well as VV, the lungs of mice tend to collapse over time; therefore, the goal of th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2010